Peritoneal surface malignancy refers to cancers that involve the peritoneum, the thin lining of the abdominal cavity. For patients seeking Peritoneal surface malignancy treatment Mumbai, these cancers may develop in the peritoneum itself or spread from other organs, including the colon, appendix, stomach, ovary, or other parts of the abdomen. Because peritoneal cancer can involve multiple areas within the abdominal cavity, diagnosis and treatment often require specialized surgical assessment and a carefully planned multidisciplinary approach.
For patients seeking Peritoneal surface malignancy treatment Mumbai, Dr. Chintamani Godbole offers specialized expertise in colorectal and peritoneal oncology, including cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). His training in colorectal surgery and peritoneal malignancy surgery in India and the UK supports an individualized approach to patients with selected advanced abdominal cancers.
Peritoneal surface malignancy may occur when cancer cells spread across the peritoneal lining and form multiple deposits within the abdominal cavity. This condition is sometimes described as peritoneal carcinomatosis. Depending on the origin, extent, biology, and distribution of the cancer, treatment may involve systemic chemotherapy, surgery, HIPEC, or a combination of therapies.
Cytoreductive surgery aims to remove visible cancer deposits from the abdominal cavity. In selected patients, surgery may be followed by HIPEC, in which heated chemotherapy is circulated inside the abdomen to target microscopic cancer cells that may remain after visible disease has been removed.
The source treatment page specifically describes CRS followed by HIPEC for selected cancers involving the peritoneal cavity, including appendiceal cancer, pseudomyxoma peritonei, colon cancer, gastric cancer, ovarian cancer, and peritoneal mesothelioma.
Cytoreductive surgery, or CRS, is a specialized procedure designed to remove visible tumour deposits from the peritoneal cavity. Depending on where the cancer has spread, the operation may involve removing portions of the peritoneum or affected abdominal organs.
The extent of surgery varies from patient to patient. In some cases, removal of involved portions of the small or large intestine, gallbladder, spleen, or abdominal lining may be required to achieve adequate tumour clearance. The surgical plan is determined after evaluating the cancer’s location, spread, overall health, and suitability for treatment.
For someone exploring Peritoneal surface malignancy treatment Mumbai, understanding that CRS is different from conventional abdominal cancer surgery is important. Peritoneal disease was historically considered difficult to treat surgically in many cases; however, selected patients may be considered for cytoreductive surgery with or without HIPEC after detailed specialist assessment.
HIPEC stands for Hyperthermic Intraperitoneal Chemotherapy. It is generally performed after cytoreductive surgery when the visible tumour deposits have been removed as thoroughly as possible.
During HIPEC, a heated chemotherapy solution is circulated within the abdominal cavity. The treatment page states that the solution is maintained at approximately 42–43°C. The objective is to expose the abdominal cavity to chemotherapy and target microscopic malignant cells that may remain following surgery.
CRS and HIPEC are therefore complementary components of treatment in appropriately selected patients. CRS addresses visible disease, while HIPEC is intended to treat residual microscopic cancer cells.
Not every patient with peritoneal cancer is suitable for cytoreductive surgery and HIPEC. Careful patient selection is essential. The medical team may consider factors such as:
The primary cancer and its biological characteristicsThe extent and distribution of peritoneal diseaseWhether the visible disease can be adequately removedInvolvement of other abdominal organsPrevious cancer treatmentsGeneral health and ability to undergo major surgeryResponse to chemotherapy or other treatments